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These effects, together with a prior report exhibiting that a small-molecule ACKR3 agonist CCX771 exhibits anxiolytic-like conduct in mice,2 assist the notion of concentrating on ACKR3 as a novel approach to modulate the opioi… Read More

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This compound was also analyzed for mu-opioid receptor exercise, and like conolidine, was identified to obtain no activity at the website. Employing exactly the same paw injection examination, various choices with increased ef… Read More